Croatian National TB Reference laboratory
WHO Supranational Reference laboratory since 2007

Croatian National Tuberculosis Laboratory Network

• CNIPH in 2007: 12088 samples (10464 smears, 12088 cultures, 1189 DST); 855 isolates typed by MIRU-VNTR

Croatian National Mycobacterium Reference Laboratory (NRL)

• activities as the level III Mycobacterium Laboratory
  • detection and identification of mycobacterial isolates
  • DST - 1^st and 2^nd line drugs
  • DNA genotyping (MIRU-VNTR method) - prospective study, detection of cross-contamination, transmission detection
  • IGRA - latent TB infection detection
  • advisory service for diagnostic laboratories and physicians
  • inquiries on the diagnostics, epidemiology and therapy of TB
• training center for guests from neighboring countries
• involvement in the national and supranational quality control via WHO-controlled laboratory network

TB diagnostics in CNIPH (2007)